Table 1.

Comparison Between NNT Computed from the Simple Proportion of Liver Failure with That from More Proper Cumulative Incidence Based on the Kaplan–Meier Approach for the Hypothetical Three-arm 1-Year Trial of 3,000 Patients with the (Imaginary) Iron Overload Syndrome.

Using Kaplan–Meier Approach Using Simple Proportion
Treatment Number of Patients Number with Liver Failure 1-Year Cumulative Incidence Number Needed to Treat 1-Year Cumulative Incidence Number Needed to Treat
Placebo 1000 324 0.454 0.324

Fedom 1000 230 0.286 6 0.230 11

Feclad 1000 238 0.441 77 0.238 12
RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2015 July; 6(3): e0033. ISSN: 2076-9172
Published online 2015 July 30. doi: 10.5041/RMMJ.10218