PubMed Central, : RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2011 April; 2(2): e0047. ISSN: 2076-9172Published online 2011 April 30. doi: 10.5041/RMMJ.10047.

Table 1.

Patient studies which demonstrated that Hp 2-2 diabetics are at a higher risk for the development of vascular disease than Hp 1-1 diabetics.

STUDY	OUTCOME
Strong Heart Study¹⁶	3–5 fold increase in CVD* in Hp 2-2
Munich Percutaneous Coronary Intervention (PCI) Study¹⁷	2.3 fold increase in MI* in Hp 2-2
Rambam post MI study¹⁸	3–5 fold increase in death or congestive heart failure in Hp 2-2
Israel Cardiovascular Reduction Events (ICARE)¹⁹	2.3 fold increase in CVD in Hp 2-2
Heart Outcomes Prevention Evaluation (HOPE)²⁰	2.3 fold increase in CVD in Hp 2-2
Womens’ Health Study (WHS)²¹	1.5 fold increase in CVD in Hp 2-2
Epidemiology of Diabetes Complications (EDC)²²	2.1 fold increase in CVD in Hp 2-2

CVD, cardiovascular disease; Hp, Haptoglobin; MI, myocardial infarction.

RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2011 April; 2(2): e0047. ISSN: 2076-9172

Published online 2011 April 30. doi: 10.5041/RMMJ.10047.