Schematic representation of accomplishments across five domains of genomics research. The progression from understanding the structure of genomes to improving the effectiveness of health care in five sequential, overlapping domains is indicated along the top. Genomic accomplishments across the domains are portrayed by hypothetical, highly schematized density plots (each blue dot reflecting a single research accomplishment, with green, yellow, and red areas reflecting sequentially higher density of accomplishments). Separate plots are shown for four time intervals: The human genome project (1990–2003), the period 2004–2010 described in the 2003 vision of the National Human Genome Research Institute (NHGRI), the period 2011–2020 described in the article by Green et al,⁵ and the open-ended future beyond 2020. Figure included with permission from Nature Publishing Group (Green ED, Guyer MS, National Human Genome Research Institute. Nature 2011;470:206).⁵