Table 1.

Assessments to Consider in Patients with Fibromyalgia or Medically Unexplained Symptoms.

Assessment Tool or Test Indication
Questionnaires Generalized Anxiety Disorder 7-item questionnaire Anxiety
Patient Health Questionnaire 9-item assessment Depression
Laboratory Studies Complete blood cell count Fatigue
Aspartame aminotransferase and alanine aminotransferase Fatigue
Bilirubin Pruritus
Hemoglobin A1c and fasting glucose Fatigue, burning mouth
Vitamin B1, B2, B6, B12 Paresthesias, burning mouth
Vitamin C, ascorbic acid Burning mouth
Vitamin D Pain
Folate Burning mouth
Ferritin Burning mouth, pruritus
Thyroid-stimulating hormone Fatigue, burning mouth
Testosterone (men) Fatigue
Morning cortisol Fatigue
Sedimentation rate, C-reactive protein Arthralgias, myalgias
Complement, total and C4 Pruritus
Antinuclear antibody Burning mouth
Sjögren syndrome antigen A and B Burning mouth
Immunoglobulins A, M, G Burning mouth, possible immunodysfunction
Tissue transglutaminase antibodies Food intolerance, irritable bowel, diarrhea
Protein electrophoresis Paresthesias, pruritus
Heavy metals Paresthesias
Metanephrines, serum Indeterminate spells
Tests Echocardiogram Exertional fatigue
Electromyogram Paresthesias
Holter monitor Palpitations, non-specific dizziness, lightheadedness
Overnight oximetry Fatigue
Spirometry with bronchodilator Dyspnea
Tilt table test Postural orthostatic tachycardia syndrome, chronic fatigue, lightheadedness
RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2015 April; 6(2): e0020. ISSN: 2076-9172
Published online 2015 April 29. doi: 10.5041/RMMJ.10204.