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Figure 3.   Patient with IgG-kappa Essential Monoclonal Gammopathy

Corneal button from a penetrating keratoplasty was prepared for histological examination. (A) This image is in the same area as the image in Figure 2 and indicates the deposition of Ig composed of kappa light chains by the immunoperoxidase reaction (brown stain). (B) Transmission electron microscopy uncovered electron-dense extracellular deposits in the same area that exhibited a honeycomb pattern or parallel linear structures with a periodicity of 10–11 nm (original magnification ×27,000). (Used from reference 7 with permission of Archives of Ophthalmology.)

RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2015 July; 6(3): e0026. ISSN: 2076-9172
Published online 2015 July 30. doi: 10.5041/RMMJ.10211