Table 2.

Hemodynamic and Indices of Autonomic Function Before and After Ivabradine.

Parameter Baseline Ivabradine
Rest Tilt Rest Tilt
HR (bpm) 70±3 118±4 66±2* 101±5*
Systolic BP (mmHg) 113±5 114±4 114±3 115±4
Diastolic BP (mmHg) 68±3 75±3 67±3 74±4
Valsalva ratio 1.43±0.1 - 1.52±0.2 -
RMSSD 35±4 16±2 28±6 18±2
Lfrri 715±160 470±180 790±150 390±120
Hfrri 790±120 180±80 840±140 210±90
Lfrri/Hfrri ratio 1.15±0.2 3.9±1.0 0.95±0.1 4.1±1.2
LfBP 1.5±0.6 5.1±1.2 1.6±0.5 4.7±1.0
*Significant differences between the baseline and the tilt.

BP, blood pressure; bpm, beats per minute; Hfrri, RR intervals high-frequency domain; HR, heart rate; LfBP, BP low-frequency domain; Lfrri, RR intervals low-frequency domain; RMSSD, root mean square of the successive differences.

RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2015 July; 6(3): e0028. ISSN: 2076-9172
Published online 2015 July 30. doi: 10.5041/RMMJ.10213.