Patient Demographics Parameters.
Patient Demographics Parameters.
| Demographic Parameter | Neoadjuvant Chemotherapy (NACT, n=35) | Neoadjuvant Chemoradiotherapy (NACRT, n=35) | P value |
|---|---|---|---|
| Median age in years (range) | 54 (23–70) | 53 (26–70) | 0.7199 |
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| Gender | |||
| Male | 20 (57%) | 18 (54%) | 0.8106 |
| Female | 15 (43%) | 17 (46%) | |
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| Median symptom duration in months (range) | 2 (0.5–12) | 1.25 (0.5–12) | 0.4561 |
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| ECOG PS score | |||
| 0 | 31 (88.5%) | 34 (97%) | 0.3565 |
| 1 | 4 (11.5%) | 1 (3%) | |
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| BMI (kg/m2) (median) | 20 | 24.17 | 0.0602 |
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| Tumor site | |||
| Middle esophagus | 5 (14%) | 11 (31.4%) | 0.2983 |
| Lower esophagus (Siewert I)* | 12 (32%) | 12 (34.2%) | |
| Esophago-gastric junction (Siewert II) | 6 (17%) | 3 (8.5%) | |
| Subcardial (Siewert III) | 12 (34.2%) | 9 (25.7%) | |
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| Tumor type | |||
| Adenocarcinoma | 16 (45.7%) | 12 (34%) | 0.4451 |
| Squamous cell carcinoma | 19 (54.3%) | 21 (60%) | |
| Others | 0 | 2 (6%) | |
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| Tumor in cm | |||
| Median | 6 | 6 | 0.3656 |
| Range | 2.5–8 | 2.5–8 | |
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| Tumor thickness in cm | |||
| Median | 1.85 | 2 | 0.362 |
| Range | 0.6–5.7 | 0.7–4 | |
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| T stage | |||
| Early T stage cT1/2 | 2 (5.8%) | 2 (5.8%) | 1 |
| Advanced T stage cT3/4 | 33 (94.2%) | 33 (94.2%) | |
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| Clinical N stage | |||
| Node negative | 19 (54.3%) | 15 (43%) | 0.4734 |
| Node positive | 16 (45.7%) | 20 (57%) | |