Elastic Fiber Parameters for Varying Grades of Oral Squamous Cell Carcinoma (OSCC) and Epithelial Dysplasia.
Elastic Fiber Parameters for Varying Grades of Oral Squamous Cell Carcinoma (OSCC) and Epithelial Dysplasia.
| Fiber Parameter | Chi-square (P value) | Mild Dysplasia (n=20) | Moderate Dysplasia (n=20) | Severe Dysplasia (n=20) | Well-diff. OSCC (n=20) | Moderately Diff. OSCC (n=20) | Poorly Diff. OSCC (n=20) |
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| Elastic fiber density | 114.33 (<0.001) | ||||||
| Scanty | – | 4 | 20 | 12 | – | 20 | |
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| Moderate | 18 | 16 | – | 8 | 6 | – | |
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| Abundant | 2 | - | 6 | - | 14 | – | |
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| Morphology | 120.00 (<0.001) | ||||||
| Short, thick, wavy | 20 | 20 | - | 20 | 20 | – | |
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| Long, thin, straight | - | - | 20 | - | - | 20 | |
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| Grouping pattern | 10.17 (0.071) | ||||||
| Single | 18 | 20 | 20 | 20 | 20 | 20 | |
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| In bunches | 2 | – | - | - | - | - | |
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| Staining intensity | 93.9 (<0.001) | ||||||
| Weak | 14 | 2 | 2 | 2 | – | 2 | |
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| Moderate | 2 | 12 | 16 | 16 | 4 | 16 | |
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| Strong | 4 | 6 | 2 | 2 | 16 | 2 | |
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| Orientation to overlying epithelium | 75.16 (<0.001) | ||||||
| Parallel | 20 | 20 | – | 16 | 14 | 4 | |
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| Perpendicular | – | – | 20 | 4 | 6 | 16 | |
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| Orientation to tumor islands | 20.04 (<0.001) | ||||||
| Parallel | NA | NA | NA | 18 | 6 | 4 | |
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| Haphazard | NA | NA | NA | 2 | 14 | 16 | |