Table 1.

Elastic Fiber Parameters for Varying Grades of Oral Squamous Cell Carcinoma (OSCC) and Epithelial Dysplasia.

Fiber Parameter Chi-square (P value) Mild Dysplasia (n=20) Moderate Dysplasia (n=20) Severe Dysplasia (n=20) Well-diff. OSCC (n=20) Moderately Diff. OSCC (n=20) Poorly Diff. OSCC (n=20)
Elastic fiber density 114.33 (<0.001)
 Scanty 4 20 12 20

 Moderate 18 16 8 6

 Abundant 2 - 6 - 14

Morphology 120.00 (<0.001)
 Short, thick, wavy 20 20 - 20 20

 Long, thin, straight - - 20 - - 20

Grouping pattern 10.17 (0.071)
 Single 18 20 20 20 20 20

 In bunches 2 - - - -

Staining intensity 93.9 (<0.001)
 Weak 14 2 2 2 2

 Moderate 2 12 16 16 4 16

 Strong 4 6 2 2 16 2

Orientation to overlying epithelium 75.16 (<0.001)
 Parallel 20 20 16 14 4

 Perpendicular 20 4 6 16

Orientation to tumor islands 20.04 (<0.001)
 Parallel NA NA NA 18 6 4

 Haphazard NA NA NA 2 14 16
RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2019 July; 10(3): e0014. ISSN: 2076-9172
Published online 2019 July 18. doi: 10.5041/RMMJ.10367.