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Figure 5.   In a Porcine Model of MI, hESC-CMs Demonstrated Engraftment but no Functional or Structural Improvements

Islands of engrafted cells were seen in immunosuppressed pigs receiving hESC-CMs by magnetic resonance imaging (A) and immunostaining (B). The hESC-CM-injected pigs demonstrate no reduction in scar size (C) or improvement in LVEF (D). Adapted from Romagnuolo et al.14 [CC BY 4.0].

RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2020 April; 11(2): e0015. ISSN: 2076-9172
Published online 2020 April 29. doi: 10.5041/RMMJ.10401