PubMed Central, : RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2020 July; 11(3): e0027. ISSN: 2076-9172Published online 2020 July 31. doi: 10.5041/RMMJ.10418.

Table 5.

Vaccines for Pandemic Diseases.^*

Disease	R₀	Vaccine(s)	Current Number of Cases/Year
Smallpox	3.5–6	Yes^†	None
Measles	12–18	Yes^†	5M
Plague	^‡	Yes^†	0.5K
Cholera	^‡	Yes^†	1.4–4M
Yellow fever	^‡	Yes^§	200K
Influenza H1N1	1.4–2.8	Yes^†	>5M; various types of influenza
Influenza H3N2	1.5	Yes^†	>5M; various types of influenza
Influenza H2N2	1.5	Yes^†	>5M; various types of influenza
AIDS	^‡	None	1.7M
SARS	0.19–1.08	None	None
Ebola	1.5–1.9	Yes^†	0–several thousands
MERS	0.3–0.8	None	0–0.3K
COVID-19	2.5	None	>10M^**

^*Only approved vaccines are included.

^†Various types available.

^‡Difficult to assess.

^§Live attenuated vaccine, single shot gives life-time immunity.

^**During a 6-month period.

AIDS, acquired immune deficiency syndrome; COVID-19, coronavirus disease 2019; H1N1, hemagglutinin-1 neuraminidase-1; H2N2, hemagglutinin-2 neuraminidase-2; H3N2, hemagglutinin-3 neuraminidase-2; K, thousands; M, millions; MERS, Middle East respiratory syndrome; R₀, basic reproduction number; SARS, severe acute respiratory syndrome.

RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2020 July; 11(3): e0027. ISSN: 2076-9172

Published online 2020 July 31. doi: 10.5041/RMMJ.10418