Table 2.

Comparison of ALDH1, SOX2, CD44, OCT4, and p16 Immunoexpression between the OED and Normal Groups.

Marker OED Group Score (Mean±SD) Normal Group Score (Mean±SD) P Value
ALDH1 5.00±3.84 0.62±1.24* 0.001
SOX2 4.42±3.81 1.62±2.05* 0.031
CD44 7.29±4.08 9.10±3.84 0.206
OCT4 2.15±2.55 3.09±3.54 0.410
p16 2.14±2.40 1.52±1.15 0.436
*P<0.05 significant when comparing the OED and Normal groups.

ALDH1, aldehyde dehydrogenase 1; CD44, cluster of differentiation 44; OCT4, octamer-binding protein 4; OED, oral epithelial dysplasia; SOX2, sex-determining region Y-box 2.

RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2021 October; 12(4): e0028. ISSN: 2076-9172
Published online 2021 October 25. doi: 10.5041/RMMJ.10451
Copyright: © 2021 Alpua et al.