PubMed Central, : RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2022 January; 13(1): e0003. ISSN: 2076-9172Published online 2022 January 27. doi: 10.5041/RMMJ.10460.

Parameters	Controls (n=31)	DcSSc (n=6)	LcSSc (n=10)	SLE (n=5)	MCTD (n=5)	DM (n=4)	UCTD (n=1)	Cases (n=31)	P Value
Mean loop length (μm)	282.97± 28.94	248.17±77.57	216.50±80.25	228.60±35.47	217.60±45.86	235±25.83	173	225.74±60.79	0.002^*
Mean loop width (μm)	13.13±3.44	25±19.92	40.50±21.79	34.20±16.63	19.20±7.53	19.50±12.12	12.0	29.42±18.90	0.0001^*
Mean capillary density (/mm)	7.39±1.3	3.0±1.55	4.7±2.06	6.6±2.88	3.2±2.28	5.0±2.16	9.0	4.61±2.47	0.0001^*
Tortuosity % (n)	10% (3)	100% (6)	80% (8)	80% (4)	60% (3)	50% (2)	100% (1)	77% (24)	0.0001^†
Giant capillary % (n)	0% (0)	16.6% (1)	40% (4)	40% (2)	0% (0)	0% (0)	0% (0)	22.6% (7)	0.004^†
Dilated capillary % (n)	0% (0)	33.3% (2)	40% (4)	40% (2)	60% (3)	25% (1)	0% (0)	38.7% (12)	0.0001^†
Microhemorrhage % (n)	0% (0)	0% (0)	20% (2)	40% (2)	0% (0)	25% (1)	0% (0)	16% (5)	0.005^†
Neoangiogenesis % (n)	0% (0)	66.6% (4)	50% (5)	40% (2)	40% (2)	50% (2)	0% (0)	48% (15)	0.0001^†
Avascular area % (n)	0% (0)	83.3% (5)	50% (5)	20% (1)	100% (5)	50% (2)	0% (0)	58.0% (18)	0.0001^†
Scleroderma pattern % (n)	0% (0)	66.6% (4)	60% (6)	0% (0)	60% (3)	25% (1)	0% (0)	45.1% (14)	0.0001^†
Non-specific pattern % (n)	0% (0)	33.3% (2)	30% (3)	80% (4)	40% (2)	50% (2)	100% (1)	45.1% (14)	0.0001^†

^*ANOVA test.

^†Fisher’s exact test.

DcSSc, diffuse cutaneous systemic sclerosis; DM, diabetes mellitus; LcSSc, limited cutaneous systemic sclerosis; MCTD, mixed connective tissue disease; SLE, systemic lupus erythematosus; UCTD, undifferentiated connective tissue disease.