Table 3.

Comparison of Clinical and Cardiac Parameters with Severity of Cirrhosis.

Parameters Cirrhosis Stage χ2 / F Value P Value

CTP-A (n=23) CTP-B (n=42) CTP-C (n=31)
Age (years) 47.22±8.9 46.50±12.7 47.97±8.7 0.168 0.846

Female sex 34.7% (8) 42.8% (18) 29.0% (9) 1.508 0.470

BMI (kg/m2) 23.63±2.9 23.17±3.4 24.20±4.3 0.704 0.497

Etiology
 Alcoholic 47.8% (11) 47.6% (20) 58.0% (18) 0.904 0.636
 Non-alcoholic 52.1% (12) 52.3% (22) 41.9% (13)

QTc interval (ms) 416.83±25.4 429.48±25.6 437.1±25.5 4.169 0.018*

LVH 30.4% (7) 40.4% (17) 58.0% (18) 4.421 0.110

LVEF 57.0±10.1 58.98±7.5 51.10±8.8 7.585 0.001*

Systolic dysfunction 26.0% (6) 11.9% (5) 41.9% (13) 8.598 0.014*

E/A ratio 0.97±0.3 1.03±0.4 1.05±0.4 0.341 0.731

IVRT (ms) 81.09±19.0 82.50±21.5 84.03±17.2 0.151 0.860

DT (ms) 190.96±33.7 193.64±41.1 191.84±35.8 0.043 0.958

E/e′ ratio 7.15±1.8 7.18±2.0 7.40±2.2 0.137 0.872

Diastolic dysfunction 47.8% (11) 45.2% (19) 45.1% (14) 0.048 0.976

CCM 21.7% (5) 38.0% (16) 54.8% (17) 6.118 0.047*
*Significant; χ2, chi-square test; ANOVA test.

A, late atrial filling velocity; CCM, cirrhotic cardiomyopathy; DT, deceleration time; E, early filling velocity; e′, early diastolic mitral annular velocity; F, ANOVA test; IVRT, isovolumetric relaxation time; LVEF, left ventricular ejection fraction; LVH, left ventricular hypertrophy.

RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2023 January; 14(1): e0001. ISSN: 2076-9172
Published online 2023 January 29. doi: 10.5041/RMMJ.10488