PubMed Central, : RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2023 July; 14(3): e0014. ISSN: 2076-9172Published online 2023 July 31. doi: 10.5041/RMMJ.10501.

Parameter	Temperature Measurement		P Value
Parameter	Oral (n=407)	Rectal (n=40)	P Value
Males, n (%)	180 (44.2)	14 (35.0)	0.261
Age at admission (years), mean±SD	59.78±18.58	65.91±20.18	0.049
Smoker, n (%)^*	123 (30.3)	10 (25.0)	0.485
Temperature (°C), mean±SD	37.20±0.51	37.53±0.63	<0.001
MASCC, median (IQR)	10 (9–11)	9 (8–11)	0.025
Charlson index, median (IQR)	5 (2–7)	5 (3–7)	0.861
Charlson index >4, n (%)	227 (55.8)	24 (60.0)	0.607
Ischemic heart disease, n (%)	8 (2.0)	1 (2.5)	0.818
Diabetes mellitus, n (%)	51 (12.5)	7 (17.5)	0.372
Cerebrovascular accident, n (%)	4 (1.0)	0 (0)	0.529
Chronic kidney disease, n (%)	44 (10.8)	7 (17.5)	0.204
Dementia, n (%)^†	4 (1.0)	7 (17.9)	<0.001
Bed-ridden, n (%)^†	13 (3.2)	10 (25.6)	<0.001
Hematological tumors, n (%)^*,^†	215 (53.2)	21 (53.8)	0.94
Solid tumors, n (%)^*,^†	124 (30.8)	8 (20.5)	0.184
Mucositis, n (%)^*,^†	35 (8.7)	3 (7.7)	0.836
Perianal infections, n (%)^†	9 (2.2)	1 (2.6)	0.893
Undergoing chemotherapy treatment, n (%)^*,^†	220 (54.6)	14 (36.8)	0.027
Undergoing treatment including taxanes, n (%)^†	24 (5.9)	2 (5.1)	0.837
Suspected infection as reason for admission, n (%)^*,^†	186 (45.8)	21 (53.8)	0.351
Neutrophils, mean±SD (10³/microL)	0.23±0.15	0.26±0.16	0.275
White blood cells, mean±SD (10³/microL)	4.33±6.25	2.72±3.57	0.109
Hemoglobin, mean±SD (g/dL)	10.15±2.1	9.8±2.68	0.327
Platelets, mean±SD (10³/microL)	140.60±114.79	121.85±99.85	0.319
ICU during index hospitalization, n (%)	6 (1.5)	1 (2.5)	0.618
Duration of hospitalization, median (IQR)	3 (1–5)	2 (0–6)	0.502
Release from ED, n (%)	106 (26.0)	16 (40.0)	0.059

^*Number of patients with missing data in oral group: Smoker (1); Hematological tumors (3); Solid tumors (4), Mucositis (5); Undergoing chemotherapy treatment (4); Suspected infection as reason for admission (1).

^†Number of patients with missing data in rectal group: Dementia (1); Bed-ridden (1); Hematological tumors (1); Solid tumors (1); Mucositis (1), Perianal infections (2); Undergoing chemotherapy treatment (2); Undergoing treatment including taxanes (1); Suspected infection as reason for admission (1).

ICU, intensive care unit; IQR, interquartile ratio; MASCC, Multinational Association for Supportive Care in Cancer; n, number; SD, standard deviation.