Table 2.

Patient IBS Characteristics and Treatment.

IBS Characteristic Ethnicity P Value
Arabs (n=91) Jews (n=176)
IBS subtype
 Unclassified 7 (7.7) 31 (17.6) <0.001
 With predominant diarrhea 10 (11) 69 (39.2)
 With predominant constipation 26 (28.6) 29 (16.5)
 With mixed bowel habits 48 (52.7) 47 (26.7)
Associated comorbidities/symptoms
 Bloating 88 (96.7) 149 (84.7) 0.003
 Sleep disorders 32 (35.2) 34 (19.3) 0.004
 Anxiety 28 (30.8) 31 (17.6) 0.014
 Gastroesophageal reflux disease 36 (39.6) 40 (22.7) 0.004
 Disease duration, median (IQR), years 10 (4–15) 6.5 (2.7–15) 0.06
Medication treatments
 Any medication 87 (95.6) 119 (67.6) <0.001
 Painkillers* 34 (37.4) 49 (27.8) 0.11
 Antidepressant 41 (45.1) 37 (21) <0.001
 Sleep medication 30 (33) 15 (8.5) <0.001
 Cannabis 3 (3.3) 15 (8.5) 0.10
 Probiotics 36 (39.6) 64 (36.4) 0.60
 Rifaximin 5 (5.5) 7 (4.0) 0.57
 Antidiarrheal 9 (9.9) 20 (11.4) 0.71
 Antispasmodic 34 (37.4) 41 (23.3) 0.01
 Laxative 28 (30.8) 11 (6.3) <0.001
 Pancreatic enzymes 2 (2.2) 2 (1.1) 0.60
 Fiber supplement 53 (58.2) 16 (9.1) <0.001
Non-medical treatment
Emotional support 10 (11) 40 (22.7) 0.02
Homeopathic/alternative 77 (84.6) 50 (28.4) <0.001
Psychiatric treatment 11 (12.1) 15 (8.5) 0.35
Does the treatment help?
 No 12 (13.2) 43 (29.1) 0.01
 Partially 59 (64.8) 79 (53.4)
 Yes 20 (22) 26 (17.5)
* Painkillers include non-steroidal anti-inflammatory drugs, opiates, dipyrone, paracetamol, and others.

IBS, irritable bowel syndrome; IQR, interquartile range.

Statistically significant results are indicated in BOLD, with a p-value less than 0.05.

RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2025; 16(2): e0007. ISSN: 2076-9172
Published online 2025 April 29. doi: 10.5041/RMMJ.10542