Table 1.

Inclusion and Exclusion Criteria.

Group Inclusion Criteria Exclusion Criteria
Patients
  • Age 20–70 years (male/female)
  • CVDs >1 year (hypertension, angina, myocardial infarction, heart surgery, congestive heart failure, cerebrovascular accident, hypercholesterolemia, arrhythmia*)
  • DM >1 year
  • Clinical signs of periodontitis: plaque and calculus, bleeding on probing, pocket depth ≥4 mm, tooth mobility
  • Unwilling to participate
  • Age <20 or >70 years
  • Both CVDs and DM present
  • Pregnant/lactating
  • Other systemic diseases (apart from CVDs/DM)
  • Deep dental caries
  • Poor-quality radiographs
Controls
  • Age 20–70 (male/female)
  • Good oral hygiene
  • No clinical signs of periodontitis
  • No known history of CVDs, DM, or any other chronic systemic disease
  • No deep dental caries
Same general exclusions as above
* Cardiac arrhythmias promote endothelial dysfunction, thrombogenesis, and systemic inflammation that accelerate atherosclerosis, hence they were part of the inclusion criterion for this study.
† Deep dental caries was excluded as this can act as a chronic, low-grade irritant to the pulp tissue, triggering inflammation and reparative responses that may lead to pulp stone formation.
‡ Poor quality radiographs were defined as images with inadequate clarity or contrast, where radiopaque
RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2025; 16(4): e0022. ISSN: 2076-9172
Published online 2025 October 31. doi: 10.5041/RMMJ.10557