Clinical Outcomes and Management Implications.
Clinical Outcomes and Management Implications.
| Clinical Presentation and Management Aspects | Breast Cancer (Malignancy) | IgG4-related Mastitis (IgG4-RM) |
|---|---|---|
| Initial presentation | Firm mass, skin changes, lymphadenopathy | Firm mass, skin thickening, lymphadenopathy (mimics cancer) |
| Definitive treatment | Surgical excision (lumpectomy/ mastectomy), chemotherapy, radiation | Systemic corticosteroids (prednisolone) to induce remission |
| Novel/alternative treatment | Targeted therapy, immunotherapy | Advanced immunosuppression (e.g. rituximab), or careful observation in stable cases |