Table 3.

Interrelated Effect of the Residential Altitude and Anemia State on Hb Concentration.

Sex Anemia Status Place of Residence N Hb (g/dL) RBC (106/μL) HCT (%) MCV (fL) MCH (pg) MCHC (g/dL) RDW (%)
Female Anemic Kfar Kama 290 11.05±0.83 (7.70–11.90) 4.10±0.50 (2.33–5.77) 34.10±2.51 (22.70–38.80) 84.04±8.68 (60.70–119.90) 27.27±3.10 (17.40–38.60) 32.41±1.05 (28.20–35.90) 14.78±1.73 (11.70–23.00)

Rihaniya 73 10.98±1.02 (7.40–11.90) 4.41±0.59 (3.16–5.69) 34.14±2.74 (25.60–38.70) 78.62±9.79 (58.30–96.20) 25.32±3.87 (16.80–33.00) 32.10±1.41 (28.40–36.30) 15.17±2.24 (11.90–22.60)
 β −0.07 (0.11) 0.30 (0.05) 0.08 (0.34) −5.28 (0.75) −1.93 (0.27) −0.35 (0.13) 0.43 (0.15)
P 0.500 <0.001 0.813 <0.001 <0.001 0.010 0.004

Non-anemic Kfar Kama 657 13.03±0.71 (12.00–17.00) 4.53±0.32 (3.54–6.40) 39.53±2.29 (32.60–52.00) 87.45±4.52 (62.00–106.40) 28.83±1.61 (20.10–34.50) 32.98±0.99 (29.50–36.80) 13.53±1.09 (11.10–22.60)

Rihaniya 245 13.23±0.74 (12.00–17.20) 4.64±0.36 (3.85–6.31) 40.03±2.38 (32.50–53.20) 86.51±5.14 (66.20–98.90) 28.63±1.89 (19.80–33.20) 33.09±1.11 (29.30–37.00) 13.43±0.93 (11.80–17.00)
 β 0.205 (0.05) 0.11 (0.02) 0.48 (0.17) −1.00 (0.39) −0.22 (0.14) 0.11 (0.07) −0.102 (0.080)
P <0.001 <0.001 0.006 0.009 0.110 0.103 0.203

Male Anemic Kfar Kama 122 12.27±1.37 (5.70–13.40) 4.35±0.65 (2.16–6.20) 37.64±3.99 (17.80–42.20) 87.28±7.67 (62.40–110.30) 28.46±2.84 (20.40–35.30) 32.59±1.15 (29.20–35.20) 14.45±1.73 (12.10–22.40)

Rihaniya 44 12.11±1.37 (7.60–13.40) 4.77±0.72 (3.64–6.65) 37.65±3.57 (27.20–41.90) 79.94±9.86 (57.50–94.60) 25.73±3.71 (18.80 – 30.90) 32.11±1.30 (27.90–34.30) 15.02±1.64 (12.30–18.90)
 β −0.17 (0.15) 0.39 (0.07) −0.00 (0.47) −6.83 (1.03) −2.57 (0.37) −0.48 (0.19) 0.59 (0.21)
P 0.266 <0.001 0.997 <0.001 <0.001 0.010 0.004

Non-anemic Kfar Kama 657 14.99±0.89 (13.50–18.10) 5.08±0.37 (4.03–7.20) 44.93±2.79 (38.10–53.70) 88.63±4.59 (63.20–104.20) 29.57±1.58 (20.00–34.80) 33.37±1.07 (30.20–37.00) 13.34±0.95 (11.50–24.40)

Rihaniya 245 15.13±0.89 (13.50–18.70) 5.18±0.44 (4.29–7.52) 45.36±2.78 (39.00–55.90) 87.91±5.69 (66.30–109.70) 29.35±1.97 (21.20–35.50) 33.39±1.16 (30.40–36.70) 13.30±0.82 (11.20–17.10)
 β 0.14 (0.06) 0.10 (0.03) 0.42 (0.19) −0.75 (0.42) −0.23 (0.15) 0.01 (0.07) −0.04 (0.08)
P 0.019 <0.001 0.030 0.078 0.136 0.814 0.638

Data presented as means±SD (range). Regression coefficients β (with standard error) were derived from a multivariable linear regression model adjusted for the interaction between sex, anemia status, and residence (village). Statistical significance was set at P≤0.05 and is marked in bold.

Hb, hemoglobin; HCT, hematocrit; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; N, number of participants; RBC, red blood cell count; RDW, red cell distribution width.

RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2026; 17(2): e0014. ISSN: 2076-9172
Published online 2026 April 26. doi: 10.5041/RMMJ.10574