PubMed Central, : RMMJ Rambam Maimonides Medical Journal Rambam Health Care Campus 2026; 17(2): e0015. ISSN: 2076-9172Published online 2026 April 26. doi: 10.5041/RMMJ.10575

Stakeholder	Selected Examples of Barriers and Facilitators to Deprescribing
Patient	Barriers	Belief that medication is necessary and there will be negative results after medication withdrawal
Patient	Facilitators	Desire to have a medication unprescribed
Healthcare Professional	Barriers	Belief that deprescribing would result in the onset of withdrawal symptoms or side effects Belief that deprescribing would be interpreted as a withdrawal of care Limited involvement of patients in the deprescribing decision
Healthcare Professional	Facilitators	Belief that the risk of continuing the medication outweighs the risk of deprescribing Awareness and trust in health professionals for the deprescribing of medications Involvement of patients in the deprescribing decision
Healthcare Organization	Barriers	Limited support for deprescribing interventions Limited resources and time to review drugs for deprescribing Prioritizing care of acute problems, neglecting appropriate prescribing for chronic diseases
Healthcare Organization	Facilitators	Organizational support and prioritization of multidisciplinary deprescribing interventions Adoption of computerized clinical decision support systems Adoption of quality improvement initiatives by healthcare professionals