Internal Medicine

A Young Patient with Leg Weakness and Hypokalemia—Case Report

Elias Andrawus, Irit Hochberg, and Zaher S. Azzam


A 20-year-old female patient was admitted to hospital because of bilateral leg weakness. Laboratory investigation showed metabolic alkalosis and severe hypokalemia. Differential diagnosis included mineralocorticoid or apparent mineralocorticoid excess diseases, with a high aldosterone-to-renin ratio (ARR) after correcting hypokalemia. After confirmatory tests, imaging studies revealed a unilateral adrenocortical adenoma consistent with Conn’s disease. Surgery was curative.

Rambam Maimonides Med J 2018;9(2):e0015