Clinical Case Report

A Unique Case of Myositis

Noa Hurvitz, Ariel Kenig, Asa Kessler, Narmine Elkhateeb, Yossef Lerner, Michal Zamir, and Fadi Kharouf


Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare systemic small-vessel disease, with heterogeneous clinical manifestations. While arthralgia and myalgia are common in the disease course, frank myositis is exceedingly rare. Immune-mediated necrotizing myopathy (IMNM) is a subtype of idiopathic inflammatory myopathies (IIMs), characterized by severe myositis. We report herein a case of prominent diffuse myositis with shared features of AAV and IMNM.

Rambam Maimonides Med J 2022;13(4):e0030