Objective: Idiopathic eosinophilic vasculitis has been described in previous case series as a possible manifestation of hypereosinophilic syndrome (HES) in asthma-free patients. A rare disease, it can be classified as an eosinophilic-rich, necrotizing, systemic form of vasculitis that affects vessels of various sizes in these patients. This report shares our experience with the treatment of a patient with eosinophilic vasculitis.
Case Presentation: We present the case of a 45-year-old man who suffered from idiopathic HES manifesting as digital ulcers and peripheral ischemia of both the upper and lower limbs without the involvement of other systems. Diagnosis was made after excluding the primary and secondary causes of eosinophilia. The patient responded well to both corticosteroids and mepolizumab, an interleukin-5 inhibitor, as a corticosteroid-sparing therapy.
Conclusion: Our case of HES-associated vasculitis in an asthma-free patient supports previous reports describing this rare diagnosis of idiopathic eosinophilic vasculitis in recent years. We describe a good response to mepolizumab (interleukin-5 inhibitor) in our patient.
When patients undergoing ventral or incisional hernia repair are reoperated for recurrence with an incidence rate of 16.0% following open repair and 18.8% following minimally invasive repair, it is time for re-evaluation of the real benefit of laparoscopy in ventral hernia repair.
The recently published paper “US Medical Schools’ 2024 Commencements and Antisemitism: Addressing Unprofessional Behavior” discusses antisemitism expressions and unprofessional behavior in US medical schools’ 2024 commencement ceremony. While we share the authors’ concerns regarding rising antisemitic, anti-Palestinian and anti-Muslim bias, alongside hateful behavior toward minorities and immigrants in the US in general and in medical schools in particular, we are also concerned about the significant bias informing this paper. The authors mistakenly conflate antisemitism with harsh criticism of Israeli government and the actions of its military, and legitimate acts of solidarity with people under oppression. This fallacy is further aggravated by serious concerns (mentioned by the authors themselves) involving the paper’s methodological and statistical shortcomings. Ultimately, the paper lacks scientific rigor and appears to be ideologically motivated rather than a contribution to objective research. Scholars worldwide, Jews and Israelis amongst them, have demonstrated that these are legitimate protests, and the interpretation of their messaging as antisemitic is just another way to silence Palestinian voices calling for freedom and liberation, and delegitimizing critique on the Israeli government. This paper aims to provide the reader with currently published evidence and scientific controversy regarding this issue, that the discussed paper failed to mention.
Medicine in the Middle Ages was, and ever since remained, one of the main preoccupations of the professionally restricted Jews. One of the medical dynasties on the Iberian peninsula was the Bueno (Bonus) family. Following the expulsion of the Jews from Spain and their spread in Europe, these Iberian physicians became successful everywhere—just as the Buenos were in the Netherlands.
