Special Fifth Anniversary Issue
EDITORIAL
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Fifth Anniversary of Rambam Maimonides Medical Journal: From Concept to Action and Success
Shraga Blazer, Karl L. Skorecki, and Rafael Beyar
NOBEL LAUREATE PERSPECTIVE
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The Egg and the Nucleus: A Battle for Supremacy
J. B. Gurdon
CLINICAL IMPLICATIONS OF BASIC RESEARCH
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Lung Edema Clearance: Relevance to Patients with Lung Injury
Zaher S. Azzam and Jacob I. Sznajder
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Role of Regulatory T Cells (Treg) and the Treg Effector Molecule Fibrinogen-like Protein 2 in Alloimmunity and Autoimmunity
Andrzej Chruscinski, Hassan Sadozai, Vanessa Rojas-Luengas, Agata Bartczak, Ramzi Khattar, Nazia Selzner, and Gary A. Levy
MONOCLONAL GAMMOPATHY
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Unusual Manifestations of Monoclonal Gammopathy: I. Ocular Disease
Sophia R. Balderman and Marshall A. Lichtman
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Unusual Manifestations of Essential Monoclonal Gammopathy. II. Simulation of the Insulin Autoimmune Syndrome
Marshall A. Lichtman and Sophia R. Balderman
ORIGINAL RESEARCH
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The Effect of Ivabradine on the Heart Rate and Sympathovagal Balance in Postural Tachycardia Syndrome Patients
Merav Barzilai and Giris Jacob
MULTIDISCIPLINARY APPROACH TO PREVENTIVE MEDICINE
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The Envy of Scholars: Applying the Lessons of the Framingham Heart Study to the Prevention of Chronic Kidney Disease
Walter G. Wasser, Amnon Gil, and Karl L. Skorecki
TECHNOLOGICAL INNOVATIONS IN MEDICINE
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The Long and Winding Road to Innovation
Rafael Beyar
JEWISH ETHICS IN MEDICINE
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Risky Treatments: A Jewish Medical Ethics Perspective
Avraham Steinberg
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Mitochondrial Replacement Therapy: Halachic Considerations for Enrolling in an Experimental Clinical Trial
Rabbi Moshe D. Tendler and John D. Loike
DATA INTERPRETATION IN CLINICAL RESEARCH
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The Number Needed to Treat: 25 Years of Trials and Tribulations in Clinical Research
Samy Suissa
LETTERS TO THE EDITOR
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Letter to the Editor: Professionalism—The Role of Quality Improvement
Kieran Walsh
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Reply to Professionalism—The Role of Quality Improvement
Paul S. Mueller
CORRECTION
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Rambam Maimonides Med J 2010;1(2):e0011
Correction for the article “Why Do We Need Multifunctional Neuroprotective and Neurorestorative Drugs for Parkinson’s and Alzheimer’s Disorders?” by Moussa B. H. Youdim
Mussa Youdim
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Rambam Maimonides Med J 2010;1(2):e0015
MRI-Guided Electrophysiology Intervention
Henry Halperin and Aravindan Kolandaivelu